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Benign Nail Growths

Many different types of noncancerous, benign growths can affect the nail unit. Some of these growths can deform the nail plate, cause discoloration of the nail plate or elevate the nail plate as a growth develops underneath the nail plate. Nail tumors can originate from the nail matrix (the root of the nail), the nail bed, or the underlying tissues including the bone. Below is a list of common nail growths and tumors treated by board-certified dermatologists at Apex Skin Center.

Onychopapilloma is a rare benign tumor that originates in the nail bed, the tissue beneath the nail plate. This growth typically presents as a red line visible in the nail plate, a split of the nail plate, and a small, flesh-colored or pinkish growth that protrudes from the nail bed at the edge of the nail. While onychopapilloma is generally harmless and noncancerous, it can be cosmetically bothersome and may cause discomfort or pain, particularly if it interferes with nail growth or becomes irritated. The exact cause of onychopapilloma is not fully understood, but factors such as trauma, chronic inflammation, or genetic predisposition may contribute to its development. The diagnosis of onychopapilloma is usually made through clinical examination and may be confirmed with a biopsy to rule out other nail tumors or malignant growths. A biopsy may occasionally be recommended to rule out nail unit squamous cell carcinoma. Treatment options for onychopapilloma typically involve surgical excision to remove the tumor and restore the normal appearance and function of the affected nail.

Onychomatricoma is a rare benign tumor that affects the nail matrix, the nail root tissue responsible for nail growth. This growth typically presents as a firm, flesh-colored or pinkish nodule beneath the nail plate at the nail root with yellow discoloration, thickening, and distortion of the affected nail. Onychomatricoma is believed to arise from an overgrowth of specialized nail matrix cells, leading to the formation of a localized mass within the nail unit. While onychomatricoma is usually noncancerous and asymptomatic, it can cause cosmetic concerns and may interfere with nail growth or cause discomfort, particularly if it becomes large or inflamed. The diagnosis of onychomatricoma is typically made through clinical examination and may be confirmed by biopsy. A biopsy may occasionally be recommended to rule out nail unit squamous cell carcinoma. Treatment options for onychomatricoma often involve surgical excision to remove the tumor and restore the normal appearance and function of the affected nail.

Digital mucous cysts of the nail unit, also known as myxoid cysts or mucous pseudocysts, are benign, fluid-filled nodules that commonly develop at the base of the fingernail or toenail. These ganglion cysts typically present as small, translucent bumps, often with a bluish hue, and may be associated with underlying joint degeneration or arthritis. Digital mucous cysts are thought to arise from the degeneration of the connective tissue surrounding the joint, leading to the formation of a cystic structure filled with gelatinous fluid. While the exact cause of these cysts is not fully understood, repetitive trauma or mechanical stress to the affected digit is believed to contribute to their development. Digital mucous cysts are typically painless and asymptomatic but can cause cosmetic concerns or discomfort if they become large or interfere with nail growth. Diagnosis of digital mucous cysts is usually made through clinical examination and may rarely need to be confirmed with imaging studies such as ultrasound or magnetic resonance imaging (MRI). Treatment options for digital mucous cysts typically involve drainage of the cyst, cryosurgery, intralesional steroids or surgical management.

Subungual glomus tumors are rare, benign growths that develop in the nail bed, specifically within the glomus body and glomus cells, specialized cells involved in temperature regulation in the skin. These tumors typically present as small, reddish-blue nodules beneath the nail plate, often causing intense pain, sensitivity to cold, and tenderness to touch. Subungual glomus tumors can lead to nail deformity, discoloration, and difficulty performing everyday activities due to the discomfort they cause. While the exact cause of these tumors is unknown, genetic factors and trauma to the nail bed are believed to play a role in their development. Diagnosis of subungual glomus tumors is typically made through clinical examination and may be confirmed with imaging studies such as ultrasound or magnetic resonance imaging (MRI). Treatment options for subungual glomus tumors usually involve surgical excision to remove the tumor and relieve symptoms.

Acquired digital fibrokeratoma is a benign, slow-growing tumor that commonly develops on the fingers or toes, particularly around the nail area. These tumors typically appear as firm, flesh-colored nodules with a rough or warty texture and a rim of scale. Oftentimes, these tumors rest on top of the nail unit causing a depression in the nail plate. Acquired digital fibrokeratomas can vary in size but are usually small, ranging from a few millimeters to a centimeter in diameter. While the exact cause of these tumors is not fully understood, they are believed to arise from trauma or chronic irritation to the skin, such as repeated friction or pressure. Acquired digital fibrokeratomas are typically painless and asymptomatic but can cause cosmetic concerns or discomfort if they become large or interfere with daily activities. The diagnosis of acquired digital fibrokeratoma is usually made through clinical examination and may be confirmed with a skin biopsy. Treatment options for acquired digital fibrokeratoma typically involve surgical excision to remove the tumor and restore the normal appearance and function of the affected digit.

Subungual bony exostosis is a rare but benign condition characterized by the development of bony growths beneath the toenail or fingernail. These growths typically originate from the bone beneath the nail and protrude upwards, causing pain, nail lifting and nail deformity. Subungual exostosis commonly presents as a firm, bony mass beneath the nail plate. While the exact cause of subungual exostosis is not fully understood, trauma or injury to the nail matrix or underlying bone is believed to play a role in its development. Diagnosis of subungual exostosis is usually made through clinical examination and may be confirmed with imaging studies such as X-rays or magnetic resonance imaging (MRI). Treatment options for subungual exostosis typically involve surgical excision to remove the bony growth and restore the normal appearance and function of the affected nail.

Early detection and treatment can help prevent complications and ensure optimal outcomes for individuals with benign nail growths. When you are concerned or bothered by a nail growth, don’t wait. At Apex Skin Center, we are here for you and your skin. Board-certified dermatologist and fellowship trained Mohs surgeon Dr. Thomas Knackstedt and the team at Apex Skin Center in Fuquay-Varina look forward to serving you. Contact Apex Skin Center to schedule a consultation or book your visit online in a few easy steps.

At a Glance

Dr. Thomas Knackstedt

  • Double board certified in dermatology and Mohs Surgery
  • Over ten years of experience providing evidence-based care
  • Nationally renowned physician leader with numerous publications, lectures, and academic affiliations
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